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Nonenzymatic Synthesis of RNA and DNA Oligomers on Hexitol Nucleic Acid Templates: The Importance of the A Structure

โœ Scribed by Kozlov, Igor A.; Politis, Panagiotis K.; Van Aerschot, Arthur; Busson, Roger; Herdewijn, Piet; Orgel, Leslie E.


Book ID
121409973
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
79 KB
Volume
121
Category
Article
ISSN
0002-7863

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## Abstract Highโ€resolution NMR studies of an ฮฑโ€homoโ€DNA:RNA duplex reveal the formation of a rightโ€handed parallelโ€oriented helix. It differs significantly from a standard Aโ€ or Bโ€type helix by a small twist value (26.2ยฐ), which leads to a helical pitch of 13.7 base pairs per helical turn, a negat