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Nondenaturing solubilization of β2 microglobulin from inclusion bodies by l-arginine

✍ Scribed by Mitsuo Umetsu; Kouhei Tsumoto; Shigeki Nitta; Tadafumi Adschiri; Daisuke Ejima; Tsutomu Arakawa; Izumi Kumagai


Book ID
116289842
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
491 KB
Volume
328
Category
Article
ISSN
0006-291X

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## Abstract The application of high hydrostatic pressure is an effective tool to promote dissolution and refolding of protein from aggregates and inclusion bodies while minimizing reaggregation. In this study we explored the mechanism of high‐pressure protein refolding by quantitatively assessing t