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Noncovalent Attachment of Nucleotides by FluorousFluorous Interactions: Application to a Simple Purification Principle for Synthetic DNA Fragments

✍ Scribed by Christian Beller; Willi Bannwarth


Book ID
102259169
Publisher
John Wiley and Sons
Year
2005
Tongue
German
Weight
196 KB
Volume
88
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

We report a highly efficient noncovalent immobilization of DNA fragments on surfaces by fluorous fluorous interactions. The principle was applied to a simple and straightforward purification protocol for synthetic DNA. The method is completely compatible with standard solid‐phase synthesis of DNA.