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Noncanonical TGF-β Signaling During Mammary Tumorigenesis

✍ Scribed by Jenny G. Parvani; Molly A. Taylor; William P. Schiemann

Book ID
106420285
Publisher
Springer US
Year
2011
Tongue
English
Weight
617 KB
Volume
16
Category
Article
ISSN
1083-3021

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## Abstract Growth factors and hormones are responsible for development of the mammary gland and can contribute to mammary carcinogenesis. The transforming growth factors (TGF) α and β1 demonstrate opposing effects on the mammary epithelium. TGFα is a mitogen and survival factor for mammary secreto