𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Nonbonded interactions in membrane active cyclic biopolymers. II. Ion binding by valinomycin

✍ Scribed by K. Sundaram; R. S. Tyagi

Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
493 KB
Volume
13
Category
Article
ISSN
0020-7608

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A possible mode for the capture of a cation by the carrier molecule valinomycin has been simulated. The intramolecular nonbonded energy and the binding energy for a centrally located potassium ion at different stages in the capture process have been evaluated using a method proposed earlier. Contrary to intuitive expectations the open conformation of valinomycin is also found to have a strong affinity for K^+^. There appears to be a rather high potential barrier between the open and closed symmetric conformations.

πŸ“œ SIMILAR VOLUMES

Nonbonded interactions in membrane-activ
Nonbonded interactions in membrane-active cyclic biopolymers. III. Analogs of valinomycin
✍ K. Sundaram; R. S. Tyagi πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 English βš– 302 KB

## Abstract Several analogs of valinomycin have been simulated. These are analogs obtained by changing the configuration of the amino acid and hydroxy acid residues one at a time. Nonbonded interactions have been calculated for three conformations of each analog. The electrostatic and polarization