Progress in understanding the pathogenes
โ
Richard H. Moseley
๐
Article
๐
2005
๐
John Wiley and Sons
๐
English
โ 159 KB
๐ 2 views
The pathogenesis of nonalcoholic steatohepatitis (NASH) is poorly defined. Feeding mice a diet deficient in methionine and choline (MCD diet) induces experimental NASH. Osteopontin (OPN) is a Th1 cytokine that plays an important role in several fibroinflammatory diseases. We examined the role of OPN