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Non-Viral Lipid-Based Nanoparticles for Targeted Cancer Systemic Gene Silencing

✍ Scribed by Moreira, J. N.; Santos, A.; Moura, V.; Pedroso de Lima, M. C.; Simões, S.

Book ID: 121717678
Publisher: American Scientific Publishers
Year: 2008
Tongue: English
Weight: 685 KB
Volume: 8
Category: Article
ISSN: 1533-4880
DOI: 10.1166/jnn.2008.319

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## Abstract ## Background RNA interference provides a powerful technology for specific gene silencing. Therapeutic applications of small interfering RNA (siRNA) however require efficient vehicles for stable complexation, protection, and extra‐ and intracellular delivery of these nucleic acids. Her