Non-viral gene delivery regulated by stiffness of cell adhesion substrates
β Scribed by Kong, Hyun Joon; Liu, Jodi; Riddle, Kathryn; Matsumoto, Takuya; Leach, Kent; Mooney, David J.
- Book ID
- 109933706
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 578 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1476-1122
- DOI
- 10.1038/nmat1392
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Delivering genes to mediate functions of cells is a crucial technology for both basic science and clinical applications. Though numerous non-viral gene delivery systems have been developed, the diversity of mammalian cells poses a great challenge to the material design. Here, we demonstrate that sur