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Non-steroidal anti-inflammatory drug-induced apoptosis in gastric cancer cells is blocked by protein kinase C activation through inhibition of c-myc

✍ Scribed by Zhu, G H; Lam, S K

Book ID: 110000931
Publisher: Nature Publishing Group
Year: 1999
Tongue: English
Weight: 287 KB
Volume: 79
Category: Article
ISSN: 0007-0920
DOI: 10.1038/sj.bjc.6690062

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## Abstract Genistein is an isoflavenoid found in soy that has anti‐tumorigenic activities. Treatment of colorectal carcinoma HCT‐116 cells with 50 μM genistein results in a 50% reduction in cell proliferation and a 6‐fold increase in apoptosis. Genistein induces nonsteroidal anti‐inflammatory drug