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NON-SPECIFIC INHIBITORS OF NITRIC OXIDE SYNTHASE CAUSE MYOCARDIAL NECROSIS IN THE RAT

✍ Scribed by Heitor Moreno Jr; Luciana P. Nathan; Konradin Metze; Soraia KP Costa; Edson Antunes; Stephen Hyslop; Roberto Zatz; Gilberto de Nucci

Book ID
108937035
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
411 KB
Volume
24
Category
Article
ISSN
0305-1870

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Nitric oxide synthase inhibitors improve
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✍ Laura K. Knox; Alastair G. Stewart; Peter G. Hayward; Professor Wayne A. Morriso πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 343 KB

## Abstract The ability of nitric oxide (NO) synthase inhibitors to reduce ischemia‐induced skin flap necrosis was assessed using a modified McFarlane flap in the rat. Flap survival was significantly improved in L‐NIO treated (86 Β± 2%), L‐NAME‐treated (84 Β± 2%), and aminoguanidine‐treated (76 Β± 2%)