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Non-small cell lung cancer—Smokers or non-smokers, does it matter?

✍ Scribed by Barlési, Fabrice; Nanni-Metellus, Isabelle; Breen, David; Fina, Frédéric; Astoul, Philippe; Martin, Pierre-Marie

Book ID
119320004
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
405 KB
Volume
63
Category
Article
ISSN
0169-5002

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## Abstract Mounting evidence has suggested somatic mutations in the __EGFR__ gene are associated with better responsiveness to __EGFR__ tyrosine kinase inhibitors (TKIs) in patients with non‐small‐cell lung cancer (NSCLC). Some, but not all, studies have reported that the mutations were more frequ