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Non-random distribution of instability-associated chromosomal rearrangement breakpoints in human lymphoblastoid cells

โœ Scribed by Stephen R. Moore; David Papworth; Andrew J. Grosovsky


Book ID
113808863
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
328 KB
Volume
600
Category
Article
ISSN
0027-5107

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We studied the action of deoxyribonuclease I on human lymphocytes in order to determine the localization of the DNAase induced aberrations. Our results indicate a non-random distribution of the lesions on chromosome regions which may reflect a differential pattern of sensitivity to the enzyme. Furth