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Non-pegylated liposomal doxorubicin and docetaxel in metastatic breast cancer: final results of a phase

✍ Scribed by Peter Schmid; J. Krocker; R. Kreienberg; P. Klare; K. Kittel; H. Sommer; G. Heinrich; T. Steck; W. Lichtenegger; D. Elling; S. Kümmel

Publisher: Springer
Year: 2008
Tongue: English
Weight: 246 KB
Volume: 64
Category: Article
ISSN: 0344-5704
DOI: 10.1007/s00280-008-0887-3

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## Abstract ## BACKGROUND Pegylated liposomal doxorubicin (PEG‐LD) and docetaxel have single‐agent activity in several malignancies. The authors conducted a Phase I trial to evaluate the maximum tolerated dose (MTD), toxicities, and effect of dose sequencing of this combination in patients with ad