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Non-Participation in a Randomized Controlled Trial: The Effect on Clinical and Non-Clinical Variables

✍ Scribed by Vermaire, J.H.; van Loveren, C.; Poorterman, J.H.G.; Hoogstraten, J.

Book ID
120409762
Publisher
S. Karger AG
Year
2011
Tongue
English
Weight
129 KB
Volume
45
Category
Article
ISSN
0008-6568

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In clinical trials where patients are randomized between two treatment arms, not all patients comply with the treatment they were randomly assigned to. The reasons for (non)compliance may be associated with the outcome variable and thereby act as confounders. The standard way of analysing such trial