Non-pancreatic proteases of the chymotrypsin family. II. Two proteases from a mouse mast cell tumor

Characterization of mouse mast cell prot

Characterization of mouse mast cell protease-8, the first member of a novel subfamily of mouse mast cell serine proteases, distinct from both the classical chymases and tryptases

✍ Claudia Lützelschwab; Mallen R. Huang; Marika C. Kullberg; Maria Aveskogh; Lars 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 304 KB 👁 2 views

Using a recently developed PCR-based strategy, a cDNA encoding a novel mouse mast cell (MC) serine protease (MMCP-8) was isolated and characterized. The MMCP-8 mRNA contains an open reading frame of 247 amino acids (aa), divided into a signal sequence of 18 aa followed by a 2-aa activation peptide (