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Non-movement disorder heralds symptoms of Machado-Joseph disease years before ataxia

✍ Scribed by Anelyssa D'Abreu; Joseph Friedman; Jim Coskun


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
53 KB
Volume
20
Category
Article
ISSN
0885-3185

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✦ Synopsis


Abstract

We describe three patients with the Machado‐Joseph disease (MJD) genetic abnormality who had non‐movement disorder neurological symptoms or signs that preceded the gait ataxia by several years. This implies that some clinical manifestations other than ataxia may be considered part of the herald symptoms of MJD, especially in the setting of a positive family history. © 2005 Movement Disorder Society