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Non-irradiated campherquinone induces DNA damage in human gingival fibroblasts

✍ Scribed by Joachim Volk; Christina Ziemann; Gabriele Leyhausen; Werner Geurtsen


Book ID
113565805
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
360 KB
Volume
25
Category
Article
ISSN
0109-5641

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## Abstract ## Background PhiC31 integrase facilitates efficient integration of transgenes into human and mouse genomes and is considered for clinical gene therapy. However recent studies have shown that the enzyme can induce various chromosomal abnormalities in primary human embryonic cells and m