Non-ionizable Polyacrylic Hydrogels Sensitive to pH for Biomedical Applications
✍ Scribed by Blanca Vázquez; Mariló Gurruchaga; Isabel Goñi; Julio San Román
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 317 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0959-8103
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✦ Synopsis
Hydrogels based on ethoxytriethyleneglycol monomethacrylate/methyl methacrylate (T/M) copolymers were prepared by free radical polymerization at 70¡C in bulk with azobisisobutyronitrile as initiator. The reactivity ratios were calculated by FinemanÈRoss (FR) and KelenÈTudos (KT) linearization methods and by the non-linear least square method suggested by Tidwell and Mortimer (TM). The reactivity ratios obtained were
Microstructure was obtained in terms of the distribution of T-and M-centred triads. The swelling behaviour of the hydrogels was studied by immersion of the Ðlms in water and in bu †ered solutions at various pH values and it was analysed by comparison with that of poly(ethoxytriethyleneglycol monomethacrylate). It was observed that not only the average copolymer composition but also the distribution of monomeric sequences play an important role in the swelling behaviour.