## Abstract MR thermometry based on the water ^1^H signal provides high temporal and spatial resolution, but it has low temperature sensitivity (∼0.01 ppm/°C) and requires monitoring of another weaker signal for absolute temperature measurements. The use of the paramagnetic lanthanide complex, thul
Non-invasive temperature imaging with thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetramethyl-1,4,7,10-tetraacetic acid (TmDOTMA−)
✍ Scribed by Sait Kubilay Pakin; S. K. Hekmatyar; Paige Hopewell; Andriy Babsky; Navin Bansal
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 209 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0952-3480
- DOI
- 10.1002/nbm.1010
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Gd(III) complexes of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid bearing two and four hydroxymethyl moieties on the cyclen ring were prepared to be studied as low toxicity MRI contrast agents. The key intermediates in the syntheses of the two ligands are the corresponding bis and tetras
## Abstract The ligand H~5~dotasa (=(__αRS__)‐__α__‐(carboxymethyl)‐1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetraacetic acid) is a H~4~dota‐like macrocyclic ligand with a carboxymethyl CH~2~COOH substituent at the C(__α__) atom of one of the four acetate pendant arms of H~4~dota (=1,4,7,10‐tetraaza
## Abstract Noninvasive techniques to monitor temperature have numerous useful biomedical applications. However, MR thermometry techniques based on the chemical shift, relaxation rates, and molecular diffusion rate of the water ^1^H signal suffer from poor thermal resolution. The feasibility of MR
1,4,7-Tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane is widely used as an intermediate in the preparation of medically important DO3A and DOTA metal chelators. Despite its commercial availability and importance, the literature describing the preparation and properties of the free bas