Non-invasive in vivo imaging with radiolabelled FIAU for monitoring cancer gene therapy using herpes simplex virus type 1 thymidine kinase and ganciclovir
β Scribed by Win-Ping Deng; WenK. Yang; Wen-Fu Lai; Ren-Shyan Liu; Jeng-Jong Hwang; Den-Mei Yang; Ying-Kai Fu; Hsin-Ell Wang
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 470 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0340-6997
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## Abstract We have earlier demonstrated that inhibition of polyamine biosynthesis with difluoromethylornithine (DFMO) can be used to enhance the cytotoxicity of herpes simplex virus thymidine kinase/ganciclovir (HSVβTK/GCV) gene therapy in different tumor cell lines. Here, the utility of this trea
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