Non-Hodgkin's lymphomas. VI. Results of treatment in childhood

✍ Scribed by Eli Glatstein; Hun Kim; Sarah S. Donaldson; Ronald F. Dorfman; T. John Gribble; Jordan R. Wilbur; Saul A. Rosenberg; Henry S. Kaplan

• Publisher: John Wiley and Sons
• Year: 1974
• Tongue: English
• Weight: 592 KB
• Volume: 34
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(197407)34:1<204::aid-cncr2820340131>3.0.co;2-2

✦ Synopsis

A retrospective study was undertaken reviewing records of all children seen in the Division of Radiation Therapy at Stanford University Hospital between 1961 and 1971 with a diagnosis of non-Hodgkin's lymphoma. Of 41 patients who had been originally diagnosed as having a non-Hodgkin's lymphoma, a diagnosis was confirmed in only 32. Two cases were interpreted as malignant histiocytosis, and 7 other patients were diagnosed as having Hodgkin's disease. Of the 32 patients with a non-Hodgkin's lymphoma, all but 1 had lymphoma of the diffuse type, with diffuse histiocytic lymphoma being the most common histologic diagnosis. Lymphangiography was attempted in all but 1 patient. Fifty-five percent of IStage I patients and 38% of Stage I1 patients are alive and free of disease more than ' 2 years after the completion of radiation therapy alone. There were no relapses seen after 12 months. Bone marrow involvement was seen in 5 patients at presentation and developed in an additional 8 patients following the initiation of radiation therapy.

Cancer 1974.

ECENT STUDIES ON THE NON-HODGKIN'S LYM-