Non-Hodgkin lymphoma (NHL) as a second neoplasm occurring after neuroblastoma treatment

✍ Scribed by Siegert, Elke; Weissbach, Gerhard; Fischer, Rainer; Lauterbach, Ingrid

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 269 KB
• Volume: 30
• Category: Article
• ISSN: 0098-1532
• DOI: 10.1002/(sici)1096-911x(199801)30:1<18::aid-mpo7>3.0.co;2-3

✦ Synopsis

As far as we know, this is the first report of a non-Hodgkin lymphoma developing after successful treatment of neuroblastoma. A boy was found to have a mediastinal T-cell lymphoma at the age of 5. He had been treated for a neuroblastoma of the left adrenal region 4 years before, when by intensive chemotherapy and radiation a complete remission of the pri-mary tumor was achieved. The second malignancy has also been controlled without evidence of recurrence 1 year after termination of treatment. We conclude that treatment of a neuroblastoma by cytostatic drugs and radiation may lead to a non-Hodgkin lymphoma as a second malignancy.