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Non-enzymic oligonucleotide synthesis on a polycytidylate template

✍ Scribed by Sulston, J.; Lohrmann, R.; Orgel, L.E.; Schneider-Bernloehr, H.; Weimann, B.J.; Miles, H.Todd

Book ID
122978999
Publisher
Elsevier Science
Year
1969
Tongue
English
Weight
450 KB
Volume
40
Category
Article
ISSN
0022-2836

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A simulation model is proposed for the template- and sequence-directed (TSD) condensation of two trideoxyribonucleotide 3'-phosphate molecules into a hexameric template with palindromic sequence studied experimentally by von Kiedrowski (1986;Angew. Int. Ed. Engl.25, 932--935). The model simulates re