Non-covalent Surface Interactions between Silicone and Biological Macromolecules Yield Bioreactive Substances

✍ Scribed by Nir Kossovsky

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 195 KB
• Volume: 11
• Category: Article
• ISSN: 0268-2605
• DOI: 10.1002/(sici)1099-0739(199705)11:5<353::aid-aoc595>3.0.co;2-5

✦ Synopsis

While most organometallics enter the environment through their industrial release, silicones are organometallic compounds purposefully introduced in high volume directly into healthy humans. A chemically centered study of the behavior of silicones in the biological environment reveals numerous degradative reactions and surface interactions that can produce bioreactive substances. Data from a variety of disciplines suggest that the preponderance of evidence supports the argument that silicone is a toxic organometallic.