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Non-concerted nucleophilic [4+1] cycloaddition of (dimethylamino)methoxycarbene to arylazonicotinates in the synthesis of pyrazolo[3,4-c]pyridines and pyrazolo[4′,3′:4,5]pyrido[2,3-d]pyrimidines

✍ Scribed by Behbehani, Haider; Ibrahim, Hamada Mohamed; Elnagdi, Mohamed H.


Book ID
120339316
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
461 KB
Volume
69
Category
Article
ISSN
0040-4020

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Synthesis of pyrazolo-annelated heterocy
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## Abstract magnified image A series of pyrazolo[3,4‐__b__]pyridines has been synthesized by __Friedländer__ condensation of 5‐amino‐pyrazole‐4‐carbaldehyde **1** with active methylene compounds in basic medium. Pyrazolo[4′3′:5,6]pyrido‐[2,3‐__d__]pyrimidines have been synthesized from pyrazolo[3,