In vitro neuroprotection against glutama
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M.J. Drian; J.M. Kamenka; A. Privat
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Article
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1999
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John Wiley and Sons
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English
β 540 KB
Primary cultures of embryonic cortical cells were used to test the neuroprotective effect of two novel noncompetitive N-methyl-D-aspartate antagonists against the neurotoxicity of glutamate. These two compounds, GK 11 and GK 222, are phencyclidine derivatives that contain asymetric carbon atoms. We