Non-aqueous reduction of aromatic sulfonyl chlorides to thiols using a dichlorodimethylsilane-zinc-dimethylacetamide system

✍ Scribed by Hiromi Uchiro; Susumu Kobayashi

• Book ID: 104261202
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 205 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)00408-6

✦ Synopsis

A new and efficient method for the non-aqueous reduction of sulfonyl chlorides to affored the corresponding thiols by use of a dichlorodimethylsilane-zinc-dimethylacetamide system was successfully developed Various aromatic thiols were prepared in high yield by easy operation.

Continuous reactions with the above reduction using the prepared thiol were also demonstrated.