A novel role of ERK5 in integrin-mediate
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Rajinder S. Sawhney; Wensheng Liu; Michael G. Brattain
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Article
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2009
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John Wiley and Sons
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English
β 345 KB
π 1 views
## Abstract In metastatic cancer, high expression levels of vitronectin (VN) receptors (integrins), FAK, and ERK5 are reported. We hypothesized that integrinβmediated ERK5 activation via FAK may play a pivotal role in cell adhesion, motility, and metastasis. ERK5 and FAK phosphorylation when metast