Nogo and Nogo receptor: Relevance to schizophrenia?
β Scribed by Willi, Roman; Schwab, Martin E.
- Book ID
- 122633797
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 388 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0969-9961
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The recently cloned gene Nogo, whose alternative splice products correspond to the antigenic target of the central nervous system (CNS) regeneration enhancing monoclonal antibody INβ1, codes for membrane proteins enriched in brain, particularly in oligodendrocytes. The 66βamino acid ext
Schizophrenia (SCZD) or schizoaffective disorders are quite common features in patients with DiGeorge/velo-cardio-facial syndrome (DGS/VCFS) as a result of chromosome 22q11.2 aploinsufficiency. We evaluated the Nogo-66 receptor gene (RTN4R), which maps within the DGS/VCFS critical region, as a poten