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Nodal Signaling in Xenopus Gastrulae Is Cell-Autonomous and Patterned by β-Catenin

✍ Scribed by Minako K. Hashimoto-Partyka; Masahiro Yuge; Ken W.Y. Cho


Book ID
117979422
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
499 KB
Volume
253
Category
Article
ISSN
0012-1606

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## Abstract Aberrant expression/localisation of β‐catenin has been implicated in the progression of oesophageal cancer. As a member of the Wnt‐signalling pathway, activated β‐catenin translocates into the nucleus and drives gene transcription. Insulin‐like growth factors (IGFs) have been implicated