Nod2 is expressed by myeloid blood dendritic cells, mature Nod2 mutant and wild-type blood dendritic cells induce similar T-cell phenotypes

Muramyl dipeptide–induced differential g

Muramyl dipeptide–induced differential gene expression in NOD2 mutant and wild-type crohn's disease patient–derived dendritic cells

✍ Zuzana Zelinkova; Astrid J. van Beelen; Floor de Kort; Perry D. Moerland; Emiel 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 189 KB 👁 1 views

## Background: Mutations in the gene encoding the nucleotide-binding oligomerization domain 2 (nod2) protein are associated with crohn's disease (cd), but the mechanism underlying this is not completely understood. to study the mechanism of cd resulting from nod2 mutations, we analyzed nod2-depende