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NOD2 and Crohn’s Disease: Loss or Gain of Function?

✍ Scribed by Lars Eckmann; Michael Karin


Book ID
116570467
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
233 KB
Volume
22
Category
Article
ISSN
1074-7613

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Are NOD2 polymorphisms linked to a speci
✍ Stina Rikke Jensen; Ole Haagen Nielsen; Susanne Brix 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 794 KB

The complex and yet unknown etiology of Crohn's disease (CD) might consist of various disease endophenotypes, each of which represent their own pathogenesis. This review focuses on the disease endophenotype linked to polymorphisms in the nucleotide-binding oligomerization domain containing 2 (NOD2)