Nociceptin inhibits non-adrenergic non-cholinergic contraction in guinea-pig airway
β Scribed by S Shah; C P Page; D Spina
- Book ID
- 110003836
- Publisher
- Nature Publishing Group
- Year
- 1998
- Tongue
- English
- Weight
- 277 KB
- Volume
- 125
- Category
- Article
- ISSN
- 0007-1188
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π SIMILAR VOLUMES
Several lines of evidence suggest a regulatory role for the non-adrenergic, non-cholinergic (NANC) nervous system in the airways of the guinea-pig and man. We examined NANC frequency-response characteristics (0.2-90 Hz) with respect to segmental differences and effects of cyclooxygenase-inhibition (
GABA is a known inhibitory neurotransmitter in the CNS. Recent studies have also demonstrated the presence of GABA in peripheral tissue, including lung. To delineate a role for GABA in lung, the effect of GABA and selective GABA agonists and antagonists on neuronally-induced airway contractions in g