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Nociceptin and its natural and specifically-modified fragments: Structural studies

✍ Scribed by E. Podstawka-Proniewicz; M. Kosior; Y. Kim; K. Rolka; L. M. Proniewicz

Publisher
Wiley (John Wiley & Sons)
Year
2010
Tongue
English
Weight
950 KB
Volume
93
Category
Article
ISSN
0006-3525

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Solution conformational study of nocicep
Solution conformational study of nociceptin and its 1–13 and 1–11 fragments using circular dichroism and two-dimensional NMR in conjunction with theoretical conformational analysis
✍ Lidia Klaudel; Anna Łȩgowska; Krzysztof Brzozowski; Jerzy Silberring; Jacek WΓ³jc πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 414 KB

## Abstract Conformational studies of nociceptin (NC‐NH~2~), its fully active fragment, NC(1–13)‐NH~2~, and two significantly less potent fragments, NC(1–13)‐OH and NC(1–11)‐OH, were conducted in water and TFE solutions by the employment of circular dichroism, and in DMSO‐d~6~ by 2D NMR spectroscop