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No significant association between p53 codon 72 Arg/Pro polymorphism and risk of oral cancer

✍ Scribed by Jiang, Ning; Pan, Jie; Wang, Lei; Duan, Yin-Zhong

Book ID
118302931
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
315 KB
Volume
34
Category
Article
ISSN
1010-4283

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## Abstract A single nucleotide polymorphism (SNP) at codon 72 of the __p53__ gene (Arg72Pro) alters the p53 protein structure and affects its activity. We investigated this SNP in relation to colorectal adenoma and cancer among men and women from case–control studies nested within the Nurses' Heal