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No serotonin 5-HT2A receptor density abnormality in the cortex of schizophrenic patients studied with PET

✍ Scribed by Christian Trichard; Marie-Laure Paillère-Martinot; Dominique Attar-Levy; Jérome Blin; André Feline; Jean-Luc Martinot


Book ID
119560252
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
372 KB
Volume
31
Category
Article
ISSN
0920-9964

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Alterations in the 5-HT2A receptor gene expression in the prefrontal cortex have been suggested to play a role in the pathophysiology and pharmacotherapy of schizophrenia. This study measured mRNA encoding 5-HT2A receptor in the left superior frontal gyrus from chronic elderly schizophrenics (n ϭ 21