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NO-induced motility effects in distal colon of sGCα1knockout mice

✍ Scribed by Ingeborg Dhaese; Gwen Vanneste; Patrick Sips; Emmanuel Buys; Peter Brouckaert; Romain Lefebvre


Book ID
104493293
Publisher
BioMed Central
Year
2005
Tongue
English
Weight
196 KB
Volume
5
Category
Article
ISSN
1471-2210

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NO-induced motility effects in gastric f
✍ Ingeborg Dhaese; Gwen Vanneste; Robrecht Thoonen; Peter Brouckaert; Romain Lefeb 📂 Article 📅 2007 🏛 BioMed Central 🌐 English ⚖ 191 KB

Nitric oxide (NO) is the most important relaxant neurotransmitter in the stomach. The principal target of NO is soluble guanylate cyclase (sGC), of which two physiologically prevailing isoforms exist, namely α1β1 and α2β1. The aim of this study was to investigate the role of sGC in NO-induced smooth