No hepatitis recurrence using combination prophylaxis in HBV-positive liver transplant recipients with YMDD mutants
โ Scribed by Lucio Caccamo; Raffaella Romeo; Giorgio Rossi; Mauro Maggioni; Ferdinando Radice; Giovanna Lunghi; Massimo Colombo; Luigi R. Fassati
- Book ID
- 110916284
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 80 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0934-0874
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Recurrent hepatitis B virus (HBV) infection remains a major cause of morbidity and mortality after liver transplantation. Recently, antiviral therapy, such as lamivudine, has become available for prophylaxis against HBV reactivation posttransplantation and for the treatment of HBV recurrent disease.
The optimal duration of therapy for pegylated interferon combined with ribavirin in recurrent Hepatitis C virus (HCV) following liver transplantation is not known. We wanted to determine if testing for HCV in liver tissue by reverse transcriptase polymerase chain reaction (RT-PCR) was superior in pr