No functional role of plasminogen activator inhibitor-1 in murine adipogenesis or adipocyte differentiation

Reciprocal regulation of tissue-type and

Reciprocal regulation of tissue-type and urokinase-type plasminogen activators in the differentiation of murine preadipocyte line 3T3-L1 and the hormonal regulation of fibrinolytic factors in the mature adipocytes

✍ Taiichiro Seki; Dr. Tomoko Miyasu; Toshinori Noguchi; Ayumi Hamasaki; Rika Sasak 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB

Adipose tissue expresses a variety of genes including tumor necrosis factor alpha and type-1 plasminogen activator inhibitor (PAI-1); and these factors, produced by adipocytes, may be associated with the risk of coronary events in obesity. In this study, we characterized the production of fibrinolyt