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No evidence of INI1hSNF5 (SMARCB1) and PARVG point mutations in oligodendroglial neoplasms

✍ Scribed by M. Eva Alonso; M. Josefa Bello; Jose M. de Campos; Alberto Isla; Jesús Vaquero; Manuel Gutierrez; Jose L. Sarasa; Juan A. Rey

Book ID
113512653
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
242 KB
Volume
160
Category
Article
ISSN
0165-4608

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✍ Fan Zhang; Lu Tan; Luanne M. Wainwright; Marisa S. Bartolomei; Jaclyn A. Biegel 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 160 KB

The hSNF5/INI1 gene on chromosome 22 has been implicated as a tumor suppressor gene in pediatric rhabdoid tumor, an aggressive malignancy that generally occurs in the first two years of life. The most common sites for tumor development are the brain and kidney. We and other investigators have identi