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No evidence of association between the genetic predisposition for dizygotic twinning and schizophrenia in West Africa

✍ Scribed by Giorgio Sirugo; Kunle Odunsi; Jaime Ashenbrenner; Olufemi Morakinyo; Grier Page

Book ID
119362130
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
59 KB
Volume
70
Category
Article
ISSN
0920-9964

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No evidence for allelic association betw
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Dopamine ␀-hydroxylase (DBH), the enzyme that converts dopamine to norepinepherine, has been proposed as being involved in the aetiology of schizophrenia. Previous work identified a functional polymorphism at nucleotide 910 of the DBH gene that results in a codon change in the mature protein Ala304S

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## Abstract Traditional case‐control genetic association studies utilizing unrelated probands are often used interchangeably with family‐based designs to detect genes for complex psychiatric disorders. This strategy may be limited, however, if significant phenotypic variation exists between proband