No evidence for simian virus 40 DNA sequences in malignant non-Hodgkin lymphomas
✍ Scribed by Frank Schüler; Sandra C. Dölken; Carsten Hirt; Marc T. Dölken; Renate Mentel; Lutz G. Gürtler; Gottfried Dölken
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- French
- Weight
- 115 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0020-7136
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## Abstract The simian virus SV40 (SV40), a potent DNA oncogenic polyomavirus, has been detected in several human tumors including lymphomas, mainly in diffuse large B‐cell type (DLBCL). However, a causative role for this virus has not been convincingly established. Hypermethylation in promoter reg
The Epstein-Barr virus (EBV) is associated with a proportion of Hodgkin lymphoma (HL) cases, and this association is believed to be causal. The aetiology of cases lacking EBV in the tumour cells (EBV HRS-ve), which make up the majority of cases in western countries, is obscure. It has been suggested