No evidence for linkage between COMT and schizophrenia in a French population
✍ Scribed by Michel de Chaldée; Marilys Corbex; Dominique Campion; Maurice Jay; Danièle Samolyk; Michel Petit; Florence Thibaut; Claudine Laurent; Jacques Mallet
- Book ID
- 117333853
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 64 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0165-1781
No coin nor oath required. For personal study only.
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## Freedman et al. [1997: Proc Natl Acad Sci USA 94:587-592] reported linkage in nine multiplex schizophrenia families to markers on chromosome 15, using impaired neuronal inhibition to repeated auditory stimuli (P50), a neurophysiological deficit associated with schizophrenia, as the phenotype. T
DeLisi et al. (199413) have examined the X and Y chromosomes for linkage to schizophrenia in 126 small families and report a small positive LOD score for the marker DXS7, adjacent to the MA0 locus at Xp11.4-11.3. Because of this, we have examined the DXS7 for linkage to schizophrenia using 17 pedig