B7-H3 is a potent inhibitor of human T-c
B7-H3 is a potent inhibitor of human T-cell activation: No evidence for B7-H3 and TREML2 interaction
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Judith Leitner; Christoph Klauser; Winfried F. Pickl; Johannes Stöckl; Otto Majd
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Article
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2009
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John Wiley and Sons
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English
⚖ 368 KB
👁 1 views
## Abstract B7‐H3 belongs to the B7 superfamily, a group of molecules that costimulate or down‐modulate T‐cell responses. Although it was shown that B7‐H3 could inhibit T‐cell responses, several studies – most of them performed in murine systems – found B7‐H3 to act in a costimulatory manner. In th