No effect of insulin treatment or glycemic improvement on plasma carnitine levels in type 2 diabetic patients

✍ Scribed by Pregant, P. ;Kaiser, E. ;Schernthaner, G.

• Publisher: Springer-Verlag
• Year: 1993
• Tongue: English
• Weight: 302 KB
• Volume: 71
• Category: Article
• ISSN: 1432-1440
• DOI: 10.1007/bf00184484

✦ Synopsis

Carnitine is an essential factor for the transport of long-chain fatty acids and is important for the heart muscle. A longitudinal study in type 2 diabetic patients was carried out. Carnitine levels were observed before and during metabolic intervention with dietary measures and either sulfonylurea or insulin treatment. In both treatment groups a significant glycemic improvement was observed after 3 months (insulin treatment group: hemoglobin Alo 11.3 __+ 2.8 versus 7.0 _+ 1.0; sulfonylurea treatment group; hemoglobin Alo 11.3 _+ 1.4 versus 7.3+0.9). Carnitine levels did not differ from a control group and did not change significantly during the observed period.