Noninvasive assessment of aromatic L-ami
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Onofre T. Dejesus; Christopher J. Endres; Steven E. Shelton; R. Jerome Nickles;
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Article
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2000
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John Wiley and Sons
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English
⚖ 91 KB
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The effect of aging on aromatic L-amino acid decarboxylase (AAAD) activity in rhesus monkey striatum was assessed in vivo using PET imaging. Two analogs of L-DOPA, 6-fluoro-m-tyrosine (FMT) and 6-fluoro-L-DOPA (FDOPA), were used to image rhesus monkeys of various ages. Results show that when the ani