NO-Donor Phenols: A New Class of Products Endowed with Antioxidant and Vasodilator Properties
β Scribed by Boschi, Donatella; Tron, Gian Cesare; Lazzarato, Loretta; Chegaev, Konstantin; Cena, Clara; Di Stilo, Antonella; Giorgis, Marta; Bertinaria, Massimo; Fruttero, Roberta; Gasco, Alberto
- Book ID
- 111690968
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 366 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0022-2623
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π SIMILAR VOLUMES
Nitrososydnone-5-imines and Thiazole-2-nitrosimines are susceptible to photolytic cleavage of the =N-NO bond. This can be achieved with a tungsten lamp. In water the corresponding syndnone imine salts are formed in 90% yield at 37Β°C. Only at higher temp. (7OOC) ring opening is observed. In methanol
Di-t-butylphenol derivatives were synthesized and evaluated as antioxidams and cholesterol lowering agents. When evaluat\_,~l in cholesterol-fed rabbits, the compounds were found to exhibit both properties. Of special in~a'est was the finding that several of the compounds elevated HDL cholesterol le