No discrete complexes containing DNA polymerase α activity can be solubilized from the heat-stabilized nuclear matrix prepared from HeLa S3 cells

Catalytic properties of DNA polymerase α

Catalytic properties of DNA polymerase α activity associated with the heat-stabilized nuclear matrix prepared from HeLa S3 cells

✍ Dr. Alberto M. Martelli; Renato Bareggi; Paola Narducci 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 583 KB

We have investigated whether or not ATP or other nucleoside di-and trisphosphates (including some nonhydrolysable ATP analogues) can stimulate the activity and/or the processivity of DNA polymerase a: associated with the nuclear matrix obtained from HeLa S3 cell nuclei that had been stabilized at 37