No benefits of ultrafractionation in two head-and-neck cancer cell lines with different inherent radiosensitivity
β Scribed by Nicole Boehringer-Wyss; Stuart G Clarkson; Abdelkarim S Allal
- Book ID
- 108434721
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 115 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0360-3016
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π SIMILAR VOLUMES
The authors established five cell lines from a human head and neck tumor. The five cell lines (HC-2, HC-3, HC-4, HC-7, and HC-9) exhibited different sensitivities to Adriamycin, cisplatin, bleomycin, 5- fluorouracil, vincristine, and daunomycin. The Dw was 200 ng/ml Adriamycin (doxorubicin) for HC-7
## Abstract ## Background Cisplatin treatment is beneficial for approximately 20% of patients with head and neck squamous cell carcinoma (HNSCC). Tools to predict the clinical outcome and evaluate intrinsic cisplatin sensitivity are, therefore, required. ## Methods Cisplatin sensitivity, lysosom