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No Association of the 5′Promoter Region Polymorphism of CYP17 with Breast Cancer Risk in Japan

✍ Scribed by Hamajima, Nobuyuki ;Iwata, Hiroji ;Obata, Yuichi ;Matsuo, Keitaro ;Mizutani, Mitsuhiro ;Iwase, Takuji ;Miura, Shigeto ;Okuma, Katashi ;Ohashi, Kazuhiko ;Tajima, Kazuo

Book ID
108581958
Publisher
Wiley (Blackwell Publishing)
Year
2000
Tongue
English
Weight
65 KB
Volume
91
Category
Article
ISSN
0910-5050

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Long-term exposure to oestrogens is a well-recognised risk factor for breast cancer, whereas little is known about the influence of polymorphisms of genes involved in oestrogen biosynthesis and metabolism. A candidate, containing a single bp polymorphism, T8C, (designated, A2 allele), might be the C